生物育种科学系
赵昆昆，男，汉族，1993年07月出生，河南洛阳人，中共党员，博士，讲师研究方向：花生关键农艺性状的图位克隆、分子机制解析及育种应用
电子邮箱：[email protected]
办公地址：草榴 龙子湖校区第一实验楼南513
教育与研究/工作经历
2013.09--2017.06 草榴 农学 学士
2017.09--2023.12 草榴 作物学 博士（硕博连读）
2020.10--2021.06 深圳大学 联合培养
2024.10--至今 湖南大学 博士后
2024.09--至今 草榴 草榴 讲师
科研项目
(1). 国家自然科学基金（青年科学基金项目C类），“AhARF2-AhGRF5模块调控花生籽粒大小的分子机制解析”32502022，2026/1年至2028/12年经费30万元，在研，主持；
(2). 河南省高等学校重点科研项目计划，“花生籽粒大小相关基因的挖掘与分子标记开发”26A210019，2026/1年至2027/12年经费3万元，在研，主持；
(3). 草榴 高层次人才专项支持基金，30501809，经费5万元，在研，主持；
(4). 国家重点研发计划“花生抗病优质高产宜机收新种质创制与应用”，2023YFD1202805，2023年至2028年，经费184万元，在研，参与；
(5). 国家自然科学基金联合重点项目“花生荚果长和果重驯化性状关键基因功能及分子调控机制解析”，2023年至2027年，经费256万元，在研，参与；
(6). 河南省重点研发专项“花生高产优质遗传基础解析与新品种设计育种”，221111110500，2022年至2024年，经费130万元，已结题，参与；
代表作（第一或共一）
(1). Kunkun Zhao†, Hongzhang Xue†, Guowei Li†, Annapurna Chitikineni, Yi Fan, Zenghui Cao, Xiaorui Dong, Huimin Lu, Kai Zhao, Lin Zhang, Ding Qiu, Rui Ren, Fangping Gong, Zhongfeng Li, Xingli Ma, Shubo Wan, Rajeev K. Varshney*, Chaochun Wei*, and Dongmei Yin*. Pangenome analysis reveals structural variation associated with seed size and weight traits in peanut. Nature genetics. 2025, 57(5), 1250-1261. //doi:10.1038/s41588-025-02170-w（中科院1区Top，2024年IF=31.8）；
(2). Kunkun Zhao, Jingjing Zhang, Yi Fan, Xufa Du, Shuliang Zhu, Zhongfeng Li, Ding Qiu, Zenghui Cao, Qian Ma, Yaoyao Li, Di Cao, Sasa Hu, Kai Zhao, Fangping Gong, Rui Ren, Xingli Ma, Xingguo Zhang, Dongmei Yin *. PSC1, a basic/helix-loop-helix transcription factor controlling the purplish-red testa trait in peanut. Journal of integrative plant biology. 2024, 67(5), 1364-1378. //doi.org/10.1111/jipb.13847（中科院1区Top，2024年IF=9.3）；
(3). Kunkun Zhao1, Xufa Du1, Jingjing Zhang, Yi Fan, Qian Ma, Yaoyao Li, Zenghui Cao, Di Cao, Sasa Hu, Ding Qiu, Kai Zhao, Fangping Gong, Zhongfeng Li, Rui Ren, Lin Zhang, Xingli Ma, Xingguo Zhang, Dongmei Yin*. Fine mapping of a major QTL on chromosomes 05 for pod size in cultivated peanut (Arachis hypogaea L.). The crop journal. 2024, 12(6): 1745-1753（中科院1区Top，2024年IF=6.0）；
(4). Kunkun Zhao1, Long Wang1, Ding Qiu1, Zenghui Cao, Kuopeng Wang, Zhan Li, Xiaoxuan Wang, jinzhi Wang, Qian Ma, Di Cao, Yiyao Qi, Kai Zhao, Fangping Gong, Zhongfeng Li, Rui Ren, Xingli Ma, Xingguo Zhang, Feng Yu*, Dongmei Yin*. PSW1, an LRR receptor kinase, regulates pod size in peanut. Plant biotechnology journal. 2023; 21(10):2113-2124.（中科院1区Top，2023年IF=13.8）；
(5). Kunkun Zhao, Ke Li, Longlong Ning, Jialin He, Xingli Ma, Zhongfeng Li, Xingguo Zhang, Dongmei Yin*. Genome-wide analysis of the growth-regulating factor family in peanut (Arachis hypogaea L.). International journal of molecular sciences. 2019; 20(17):4120.（中科院2区，2019年IF=4.556）；
(6). Kunkun Zhao, Xufa Du, Pan Zhang, Jiakai Song, Peiyuan Du, Qikang Wang, Dongmei Yin*. The effects of sowing peanut with shells on main agronomic traits and yield. Oil Crop Science. 2025.
合作作者论文：
(1). Zhao, K., Li, Y., Cao, Z., Tu, Y., Guo, Y., Qiu, J., Ma, X., Gong, F., Li, Z., Zhang, L., Qiu, D., Ren, R., Zhao, K., & Yin, D. (2025). The Homocysteine S-Methyltransferase Family and Functional Analysis of AhEXF4LS Resistance to Bacterial Wilt in Peanut. Journal of agricultural and food chemistry, 10.1021/acs.jafc.5c09751. Advance online publication. .
(2). Zhao, K., Li, Y., Wang, J., Tu, Y., Cao, Z., Ma, X., Gong, F., Li, Z., Zhang, L., Qiu, D., Zhang, X., Ren, R., Zhao, K., & Yin, D. (2025). Genome-wide characterization of AhBAG genes in peanut reveals their role in bacterial wilt resistance and hormone response. BMC plant biology, 25(1), 513. //doi.org/10.1186/s12870-025-06552-4
(3). Ren, R., Cao, Z., Ma, X., Li, Z., Zhao, K., Cao, D., Ma, Q., Hou, M., Zhao, K., Zhang, L., Qiu, D., Gong, F., Zhang, X., Liu, H., & Yin, D. (2025). Multi-Omics Analysis Reveals That AhNHL Contributes to Melatonin-Mediated Cadmium Tolerance in Peanut Plants. Journal of pineal research, 77(2), e70035. //doi.org/10.1111/jpi.70035.
(4). Li, Z., Cao, Z., Ma, X., Cao, D., Zhao, K., Zhao, K., Ma, Q., Gong, F., Li, Z., Qiu, D., Zhang, X., Liu, H., Ren, R., & Yin, D. (2024). Natural resistance-associated macrophage proteins are involved in tolerance to heavy metal Cd2+ toxicity and resistance to bacterial wilt of peanut (Arachis hypogaea L.). Plant physiology and biochemistry, 207, 108411. .
(5). Zhao, K., Li, Z., Ke, Y., Ren, R., Cao, Z., Li, Z., Wang, K., Wang, X., Wang, J., Ma, Q., Cao, D., Zhao, K., Li, Y., Hu, S., Qiu, D., Gong, F., Ma, X., Zhang, X., Fan, G., Liang, Z., … Yin, D. (2024). Dynamic N6 -methyladenosine RNA modification regulates peanut resistance to bacterial wilt. The New phytologist, 242(1), 231–246.
(6). Xue, H., Zhao, K., Zhao, K., Han, S., Chitikineni, A., Zhang, L., Qiu, D., Ren, R., Gong, F., Li, Z., Ma, X., Zhang, X., Varshney, R. K., Zhang, X., Wei, C., & Yin, D. (2024). A near complete genome of Arachis monticola, an allotetraploid wild peanut. Plant biotechnology journal, 22(8), 2110–2112. //doi.org/10.1111/pbi.14331.
(7). Gong, F., Cao, D., Sun, X., Li, Z., Qu, C., Fan, Y., Cao, Z., Zhao, K., Zhao, K., Qiu, D., Li, Z., Ren, R., Ma, X., Zhang, X., & Yin, D. (2024). Homologous mapping yielded a comprehensive predicted protein-protein interaction network for peanut (Arachis hypogaea L.). BMC plant biology, 24(1), 873. .
(8). Cao, Z., Li, Z., Meng, L., Cao, D., Zhao, K., Hu, S., Li, Y., Zhao, K., Ma, Q., Li, Y., Fan, Y., Ma, X., Gong, F., Li, Z., Qiu, D., Zhang, L., Zhang, X., Ren, R., & Yin, D. (2024). Genome-wide characterization of pyrabactin resistance 1-like (PYL) family genes revealed AhPYL6 confer the resistance to Ralstonia solanacearum in peanut. Plant physiology and biochemistry, 217, 109295. .
(9). Gong, F., Cao, D., Li, Z., Fan, Y., Zhang, Y., Zhang, L., Zhao, K., Qiu, D., Li, Z., Ren, R., Ma, X., Zhang, X., Zhao, K., & Yin, D. (2024). Metabolomic and Transcriptomic Analysis Reveals Flavonoid-Mediated Regulation of Seed Antioxidant Properties in Peanut Seed Vigor. Antioxidants (Basel, Switzerland), 13(12), 1497. .
(10). Cao, D., Ma, Y., Cao, Z., Hu, S., Li, Z., Li, Y., Wang, K., Wang, X., Wang, J., Zhao, K., Zhao, K., Qiu, D., Li, Z., Ren, R., Ma, X., Zhang, X., Gong, F., Jung, M. Y., & Yin, D. (2024). Coordinated Lipid Mobilization during Seed Development and Germination in Peanut (Arachis hypogaea L.). Journal of agricultural and food chemistry, 72(6), 3218–3230.
(11). Li, Z., Liu, Q., Zhao, K., Cao, D., Cao, Z., Zhao, K., Ma, Q., Zhai, G., Hu, S., Li, Z., Wang, K., Gong, F., Ma, X., Zhang, X., Ren, R., Qiu, D., Zhao, Y., & Yin, D. (2023). Dynamic DNA methylation modification in peanut seed development. iScience, 26(7), 107062. //doi.org/10.1016/j.isci.2023.107062.
(12). Kai Zhao, Rui Ren, Xingli Ma, Kunkun Zhao, Chengxin Qu, Di Cao, Qian Ma, Yingying Ma, Fangping Gong, Zhongfeng Li, Xingguo Zhang, Dongmei Yin. Genome-wide investigation of defensin genes in peanut (Arachis hypogaea L.) reveals AhDef2.2 conferring resistance to bacterial wilt. The Crop Journal, 2021,11,29, .
(13). Li, Z., Zhang, X., Zhao, K., Zhao, K., Qu, C., Gao, G., Gong, F., Ma, X., & Yin, D. (2021). Comprehensive Transcriptome Analyses Reveal Candidate Genes for Variation in Seed Size/Weight During Peanut (Arachis hypogaea L.) Domestication. Frontiers in plant science, 12, 666483. //doi.org/10.3389/fpls.2021.666483.
(14). Gao G, X Zhang, Zhao K, Ma X and Yin D*. Genome wide identification and expression analysis of patatin-like protein family members in peanut (Arachis hypogaea L.). Reproduction and Breeding, 2021.61.217. //doi: 10.1007/s10681-021-02792-1.
(15). Li P, Ma Q, Qu C, Zhu S, Zhao K, Ma X, Li Z, Zhang X, Gong F, Yin D. Genome-wide identification and expression analysis of auxin response factors in peanut (Arachis hypogaea L.). PeerJ, 2021. 9:e12319. //doi 10.7717/peerj.12319.
(16). Xingguo Zhang, Manish K. Pandey, Jianping Wang, Kunkun Zhao, Xingli Ma, Zhongfeng Li, Kai Zhao, Fangping Gong, Baozhu Guo, Rajeev K. Varshney and Dongmei Yin*. Chromatin spatial organization of wild type and mutant peanuts reveals high-resolution genomic architecture and interaction alterations. Genome Biology. 2021. 22(1):315. //doi.org/10.1186/s13059-021-02520-xIF:17.433.
(17). Ma, X., Zhang, X., Traore, S. M., Xin, Z., Ning, L., Li, K., Zhao, K., Li, Z., He, G., & Yin, D. Genome-wide identification and analysis of long noncoding RNAs (lncRNAs) duringseed development in peanut (Arachis hypogaea L.). BMC Plant Biology.2020.20:192 .
(18). Yin, D., Ji, C., Song, Q., Zhang, W., Zhang, X., Zhao, K., Chen, C. Y., Wang, C., He, G., Liang, Z., Ma, X., Li, Z., Tang, Y., Wang, Y., Li, K., Ning, L., Zhang, H., Zhao, K., Li, X., Yu, H., … Chen, Z. J. (2019). Comparison of Arachis monticola with Diploid and Cultivated Tetraploid Genomes Reveals Asymmetric Subgenome Evolution and Improvement of Peanut. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(4), 1901672. .
(19). Zhang X, Ma X, Ning L, Li Z, Zhao K, Li K, He J, Yin D. Genome-wide identification of circular RNAs in peanut (Arachis hypogaea L.). BMC Genomics. 2019. 20(1):653. //doi: 10.1186/s12864-019-6020-7.
(20). Yin D, Ji C, Ma X, Li H, Zhang W, Li S, Liu F, Zhao K, Li F, Li K, Ning L, He J, Wang Y, Zhao F, Xie Y, Zheng H, Zhang X, Zhang Y, Zhang J. Genome of an allotetraploid wild peanut Arachis monticola: a de novo assembly. Gigascience. 2018.7(6):giy066. //doi: 10.1093/gigascience/giy066.
(21). Ma X, Zhang X, Zhao K, Li F, Li K, Ning L, He J, Xin Z and Yin D*. Small RNA and degradome deep sequencing reveals the roles of microRNAs in seed expansion in peanut (Arachis hypogaea L.). Frontiers in plant science. 2018. 9(349). //doi: 10.3389/fpls.2018.00349 SCI 3-Y.
(22). Su Lixia, Ma Xingli, Zhao Kunkun, Shen Chenglong, Lou Qing, Yin Dongmei, Shan Chongxin. Carbon nanodots as stress-resistance enhancement material for peanuts. ACS Omega, 2018, 3(12). 17770-17777. //doi.org/10.1021/acsomega.8b02604.
(23). 朱树良; 赵昆昆; 高古腔; 屈成鑫; 马莹莹; 任锐; 巩方平; 李忠峰; 马兴立; 张幸果; 殷冬梅. 花生种皮颜色智能识别模型的建立与应用. 中国油料作物学报, 2022, 44(2): 324-330.
(24). 马兴立, 赵昆昆, 赵品源, 李珊珊, 马小强, 李忠峰, 张幸果, 殷冬梅.纳米碳点对花生幼苗生长及其相关生理生化指标的影响[J].华北农学报, 2019, 34(02):138-144.
(26). 李柯, 赵昆昆, 宁龙龙, 马倩, 李忠峰, 马兴立, 张幸果, 殷冬梅.花生FAD2基因CRISPR/Cas9多靶点敲除载体构建[J].山东农业科学, 2019, 51(09):56-62-67.
(27). 宁龙龙, 刘佳佳, 赵昆昆, 李柯, 李忠峰, 马兴立, 张幸果, 殷冬梅.利用AhMITE转座子标记鉴定花生F1代真伪杂种[J].山东农业科学, 2019, 51(09):63-67. (25).
(28). 李柯, 赵昆昆,宁龙龙, 马倩, 李忠峰, 马兴立, 张幸果, 殷冬梅.花生DNA快速提取方法及应用[J].山东农业科学, 2019, 51(09):68-72.
(29). 李拴柱,赵昆昆,郑青焕,等.花生荚果不同发育时期形态学和细胞学差异分析[J].种子,2025,44(05):127-134. DOI:10.16590/j.cnki.1001-4705.2025.05.127.
专利、软著、成果：
专利
(1) 殷冬梅；赵凯；任锐；张幸果；马兴立；巩方平；赵昆昆；花生AhDef2.2基因及其鉴定方法和应用，2022-5-12，国家发明专利，CN202210512244.2；
(2) 殷冬梅；赵昆昆；巩方平；马兴立；曹增辉；李忠峰；一种花生荚果大小相关的InDel分子标记及其应用，2024-4-9，国家发明专利，ZL 2023 1 0785357.4；
(3) 殷冬梅；赵昆昆; 花生种皮颜色调控相关基因AhPSC1及其相关应用，2024-5-3，国家发明专利，ZL 2023 1 1725963.3；
(4) 殷冬梅；赵昆昆；巩方平；曹增辉；邱鼎；花生荚果大小相关基因AhPSW1及其应用，2024-10-8，国家发明专利，ZL 2023 1 0785354.0。
(5) 殷冬梅；赵昆昆；一种种皮花青素调控相关的SNP分子标记及其应用，2025-3-4，国家发明专利，ZL 2024 1 0641645.7。
著作权
- 赵昆昆；殷冬梅；巩方平；马兴立；邱鼎；花生荚果不同发育时期形态和细胞学差异分析系统V1.0，2023-3-6，计算机软件著作权登记证书，2022SR0720025。
获奖成果
(1) 把金种子带回家--打造花生全产业金链条，第八届中国国际“互联网+”，国赛铜奖（证书编号：202311256，第1名）；
(2) 花生种芯、幸福万家--构筑国家粮油安全金钟罩，第九届中国国际“互联网+”，省赛二等奖（第1名）
(3) 花生种子发育遗传解析与高产优质新品种培育及应用，河南省科学技术进步一等奖（2024-J-025-R8/14，第8名）。